V68M (p.Val68Met) variant of MAPK3 (P27361)
V68M (p.Val68Met) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
V68M (p.Val68Met) variant details
- p.Val68Met
- ExAC rs776770058
- gnomAD rs776770058
- Missense
- Variant Prioritization Score for Impact Estimate 0.764
- REVEL 0.76
- CADD 26.70
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00035)
- Structural context available