V63M (p.Val63Met) variant of MAPK3 (P27361)
V63M (p.Val63Met) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
V63M (p.Val63Met) variant details
- p.Val63Met
- cosmic curated COSV53771
- 1000Genomes rs200617125
- ESP rs200617125
- ExAC rs200617125
- Missense
- Variant Prioritization Score for Impact Estimate 0.17
- REVEL 0.08
- CADD 21.80
- PolyPhen-2 0.04
- SIFT 0.23
- Most common in the 1KG:PEL population (allele frequency 0.0059)
- Structural context available