V20I (p.Val20Ile) variant of MAPK3 (P27361)
V20I (p.Val20Ile) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
V20I (p.Val20Ile) variant details
- p.Val20Ile
- TOPMed rs2073035669
- Missense
- Variant Prioritization Score for Impact Estimate 0.246
- REVEL 0.13
- CADD 18.20
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 9.4e-07)
- Structural context available