V100I (p.Val100Ile) variant of MAPK3 (P27361)
V100I (p.Val100Ile) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
V100I (p.Val100Ile) variant details
- p.Val100Ile
- ExAC rs759671938
- gnomAD rs759671938
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.07
- CADD 18.20
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available