T66N (p.Thr66Asn) variant of MAPK3 (P27361)
T66N (p.Thr66Asn) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
T66N (p.Thr66Asn) variant details
- p.Thr66Asn
- TOPMed rs2073020790
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.05
- CADD 18.60
- PolyPhen-2 0.01
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available