T43R (p.Thr43Arg) variant of MAPK3 (P27361)
T43R (p.Thr43Arg) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
T43R (p.Thr43Arg) variant details
- p.Thr43Arg
- ExAC rs781519812
- TOPMed rs781519812
- gnomAD rs781519812
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.31
- CADD 20.70
- PolyPhen-2 0.01
- SIFT 0.53
- Most common in the East Asian population (allele frequency 3e-05)
- Structural context available