T43M (p.Thr43Met) variant of MAPK3 (P27361)
T43M (p.Thr43Met) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
T43M (p.Thr43Met) variant details
- p.Thr43Met
- ExAC rs781519812
- TOPMed rs781519812
- gnomAD rs781519812
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.05
- CADD 22.50
- PolyPhen-2 0.04
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available