T17I (p.Thr17Ile) variant of MAPK3 (P27361)
T17I (p.Thr17Ile) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
T17I (p.Thr17Ile) variant details
- p.Thr17Ile
- TOPMed rs2073035911
- gnomAD rs2073035911
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.10
- CADD 15.90
- PolyPhen-2 0.00
- SIFT 0.10
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available