R94L (p.Arg94Leu) variant of MAPK3 (P27361)
R94L (p.Arg94Leu) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
R94L (p.Arg94Leu) variant details
- p.Arg94Leu
- gnomAD rs1212630199
- Missense
- Variant Prioritization Score for Impact Estimate 0.531
- REVEL 0.46
- CADD 24.20
- PolyPhen-2 0.06
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available