R84L (p.Arg84Leu) variant of MAPK3 (P27361)
R84L (p.Arg84Leu) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
R84L (p.Arg84Leu) variant details
- p.Arg84Leu
- ExAC rs757959447
- gnomAD rs757959447
- Missense
- Variant Prioritization Score for Impact Estimate 0.792
- REVEL 0.79
- CADD 29.50
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available