R67S (p.Arg67Ser) variant of MAPK3 (P27361)
R67S (p.Arg67Ser) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
R67S (p.Arg67Ser) variant details
- p.Arg67Ser
- 1000Genomes rs567762331
- ExAC rs567762331
- TOPMed rs567762331
- gnomAD rs567762331
- Missense
- Variant Prioritization Score for Impact Estimate 0.507
- REVEL 0.45
- CADD 25.90
- PolyPhen-2 0.71
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available