R67L (p.Arg67Leu) variant of MAPK3 (P27361)
R67L (p.Arg67Leu) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
R67L (p.Arg67Leu) variant details
- p.Arg67Leu
- ExAC rs772578869
- TOPMed rs772578869
- gnomAD rs772578869
- Missense
- Variant Prioritization Score for Impact Estimate 0.546
- REVEL 0.42
- CADD 23.10
- PolyPhen-2 0.03
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available