R67H (p.Arg67His) variant of MAPK3 (P27361)
R67H (p.Arg67His) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
R67H (p.Arg67His) variant details
- p.Arg67His
- ExAC rs772578869
- TOPMed rs772578869
- gnomAD rs772578869
- Missense
- Variant Prioritization Score for Impact Estimate 0.61
- REVEL 0.48
- CADD 27.80
- PolyPhen-2 0.89
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available