R64H (p.Arg64His) variant of MAPK3 (P27361)
R64H (p.Arg64His) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
R64H (p.Arg64His) variant details
- p.Arg64His
- TOPMed rs1196812695
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.08
- CADD 23.70
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available