R64G (p.Arg64Gly) variant of MAPK3 (P27361)
R64G (p.Arg64Gly) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
R64G (p.Arg64Gly) variant details
- p.Arg64Gly
- ExAC rs753070820
- TOPMed rs753070820
- gnomAD rs753070820
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- REVEL 0.13
- CADD 25.40
- PolyPhen-2 0.11
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available