R64C (p.Arg64Cys) variant of MAPK3 (P27361)
R64C (p.Arg64Cys) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
R64C (p.Arg64Cys) variant details
- p.Arg64Cys
- cosmic curated COSV53772
- ExAC rs753070820
- TOPMed rs753070820
- gnomAD rs753070820
- Missense
- Variant Prioritization Score for Impact Estimate 0.315
- REVEL 0.13
- CADD 26.50
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available