R41L (p.Arg41Leu) variant of MAPK3 (P27361)
R41L (p.Arg41Leu) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
R41L (p.Arg41Leu) variant details
- p.Arg41Leu
- gnomAD rs1437705688
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.28
- CADD 24.20
- PolyPhen-2 0.05
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available