R41H (p.Arg41His) variant of MAPK3 (P27361)
R41H (p.Arg41His) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
R41H (p.Arg41His) variant details
- p.Arg41His
- gnomAD rs1437705688
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.24
- CADD 23.00
- PolyPhen-2 0.00
- SIFT 0.16
- Most common in the Latino/Admixed American population (allele frequency 7.3e-05)
- Structural context available