P75L (p.Pro75Leu) variant of MAPK3 (P27361)
P75L (p.Pro75Leu) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
P75L (p.Pro75Leu) variant details
- p.Pro75Leu
- gnomAD rs1277805136
- Missense
- Variant Prioritization Score for Impact Estimate 0.689
- REVEL 0.60
- CADD 31.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available