P40S (p.Pro40Ser) variant of MAPK3 (P27361)
P40S (p.Pro40Ser) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
P40S (p.Pro40Ser) variant details
- p.Pro40Ser
- 1000Genomes rs555123973
- ExAC rs555123973
- gnomAD rs555123973
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.13
- CADD 21.60
- PolyPhen-2 0.00
- SIFT 0.66
- Most common in the 1KG:BEB population (allele frequency 0.0051)
- Structural context available