P25S (p.Pro25Ser) variant of MAPK3 (P27361)
P25S (p.Pro25Ser) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
P25S (p.Pro25Ser) variant details
- p.Pro25Ser
- cosmic curated COSV53773
- TOPMed rs1044163469
- Missense
- Variant Prioritization Score for Impact Estimate 0.147
- REVEL 0.15
- CADD 10.70
- PolyPhen-2 0.00
- SIFT 0.52
- Most common in the African/African-American population (allele frequency 3.4e-05)
- Structural context available