P14H (p.Pro14His) variant of MAPK3 (P27361)
P14H (p.Pro14His) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
P14H (p.Pro14His) variant details
- p.Pro14His
- ExAC rs759741789
- gnomAD rs759741789
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.29
- CADD 23.70
- PolyPhen-2 0.44
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available