M55L (p.Met55Leu) variant of MAPK3 (P27361)
M55L (p.Met55Leu) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
M55L (p.Met55Leu) variant details
- p.Met55Leu
- ExAC rs762034287
- gnomAD rs762034287
- Missense
- Variant Prioritization Score for Impact Estimate 0.205
- REVEL 0.08
- CADD 22.60
- PolyPhen-2 0.01
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1e-05)
- Structural context available