I89V (p.Ile89Val) variant of MAPK3 (P27361)
I89V (p.Ile89Val) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
I89V (p.Ile89Val) variant details
- p.Ile89Val
- ESP rs141047495
- ExAC rs141047495
- TOPMed rs141047495
- gnomAD rs141047495
- Missense
- Variant Prioritization Score for Impact Estimate 0.387
- REVEL 0.24
- CADD 22.90
- PolyPhen-2 0.34
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 0.0012)
- Structural context available