I70V (p.Ile70Val) variant of MAPK3 (P27361)
I70V (p.Ile70Val) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
I70V (p.Ile70Val) variant details
- p.Ile70Val
- ExAC rs746736375
- gnomAD rs746736375
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.30
- CADD 25.90
- PolyPhen-2 0.71
- SIFT 0.04
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available