I70M (p.Ile70Met) variant of MAPK3 (P27361)
I70M (p.Ile70Met) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
I70M (p.Ile70Met) variant details
- p.Ile70Met
- ExAC rs775457072
- gnomAD rs775457072
- Missense
- Variant Prioritization Score for Impact Estimate 0.639
- REVEL 0.64
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available