I48V (p.Ile48Val) variant of MAPK3 (P27361)
I48V (p.Ile48Val) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
I48V (p.Ile48Val) variant details
- p.Ile48Val
- gnomAD rs2073033788
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.05
- CADD 21.00
- PolyPhen-2 0.00
- SIFT 0.26
- Most common in the African/African-American population (allele frequency 2.6e-05)
- Structural context available