I48T (p.Ile48Thr) variant of MAPK3 (P27361)
I48T (p.Ile48Thr) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
I48T (p.Ile48Thr) variant details
- p.Ile48Thr
- ExAC rs766621106
- gnomAD rs766621106
- Missense
- Variant Prioritization Score for Impact Estimate 0.516
- REVEL 0.49
- CADD 27.10
- PolyPhen-2 0.65
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available