H97L (p.His97Leu) variant of MAPK3 (P27361)
H97L (p.His97Leu) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
H97L (p.His97Leu) variant details
- p.His97Leu
- gnomAD rs1229544781
- Missense
- Variant Prioritization Score for Impact Estimate 0.8
- REVEL 0.91
- CADD 28.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available