G8W (p.Gly8Trp) variant of MAPK3 (P27361)
G8W (p.Gly8Trp) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
G8W (p.Gly8Trp) variant details
- p.Gly8Trp
- TOPMed rs1275164140
- gnomAD rs1275164140
- Missense
- Variant Prioritization Score for Impact Estimate 0.459
- REVEL 0.41
- CADD 25.20
- PolyPhen-2 0.75
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.4e-05)
- Structural context available