G8R (p.Gly8Arg) variant of MAPK3 (P27361)
G8R (p.Gly8Arg) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G8R (p.Gly8Arg) variant details
- p.Gly8Arg
- TOPMed rs1275164140
- gnomAD rs1275164140
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.19
- CADD 20.70
- PolyPhen-2 0.00
- SIFT 0.26
- Most common in the East Asian population (allele frequency 0.00011)
- Structural context available