G54D (p.Gly54Asp) variant of MAPK3 (P27361)
G54D (p.Gly54Asp) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
G54D (p.Gly54Asp) variant details
- p.Gly54Asp
- Ensembl rs2151048629
- Missense
- Variant Prioritization Score for Impact Estimate 0.536
- REVEL 0.56
- CADD 25.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available