G33W (p.Gly33Trp) variant of MAPK3 (P27361)
G33W (p.Gly33Trp) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
G33W (p.Gly33Trp) variant details
- p.Gly33Trp
- cosmic curated COSV99532
- gnomAD rs865801855
- Missense
- Variant Prioritization Score for Impact Estimate 0.571
- REVEL 0.57
- CADD 27.30
- PolyPhen-2 0.97
- SIFT 0.03
- Population evidence available
- Structural context available