G26V (p.Gly26Val) variant of MAPK3 (P27361)
G26V (p.Gly26Val) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
G26V (p.Gly26Val) variant details
- p.Gly26Val
- ExAC rs775053127
- gnomAD rs775053127
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.06
- CADD 17.50
- PolyPhen-2 0.02
- SIFT 0.35
- Most common in the African/African-American population (allele frequency 3.4e-05)
- Structural context available