G21S (p.Gly21Ser) variant of MAPK3 (P27361)
G21S (p.Gly21Ser) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
G21S (p.Gly21Ser) variant details
- p.Gly21Ser
- ExAC rs773609716
- TOPMed rs773609716
- gnomAD rs773609716
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.13
- CADD 16.70
- PolyPhen-2 0.00
- SIFT 0.90
- Most common in the African/African-American population (allele frequency 3.5e-05)
- Structural context available