G21C (p.Gly21Cys) variant of MAPK3 (P27361)
G21C (p.Gly21Cys) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
G21C (p.Gly21Cys) variant details
- p.Gly21Cys
- ExAC rs773609716
- TOPMed rs773609716
- gnomAD rs773609716
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.14
- CADD 22.30
- PolyPhen-2 0.00
- SIFT 0.15
- Most common in the South Asian population (allele frequency 2.6e-05)
- Structural context available