G19E (p.Gly19Glu) variant of MAPK3 (P27361)
G19E (p.Gly19Glu) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
G19E (p.Gly19Glu) variant details
- p.Gly19Glu
- cosmic curated COSV10808
- TOPMed rs1468414653
- Missense
- Variant Prioritization Score for Impact Estimate 0.369
- REVEL 0.28
- CADD 21.20
- PolyPhen-2 0.02
- SIFT 0.40
- Most common in the Non-Finnish European population (allele frequency 2.8e-06)
- Structural context available