G12W (p.Gly12Trp) variant of MAPK3 (P27361)
G12W (p.Gly12Trp) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
G12W (p.Gly12Trp) variant details
- p.Gly12Trp
- ExAC rs767677001
- gnomAD rs767677001
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.27
- CADD 23.30
- PolyPhen-2 0.00
- SIFT 0.01
- Most common in the East Asian population (allele frequency 3.5e-05)
- Structural context available