G11V (p.Gly11Val) variant of MAPK3 (P27361)
G11V (p.Gly11Val) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G11V (p.Gly11Val) variant details
- p.Gly11Val
- cosmic curated COSV53772
- TOPMed rs955881745
- gnomAD rs955881745
- Missense
- Variant Prioritization Score for Impact Estimate 0.349
- REVEL 0.27
- CADD 18.80
- PolyPhen-2 0.02
- SIFT 0.28
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available