F76L (p.Phe76Leu) variant of MAPK3 (P27361)
F76L (p.Phe76Leu) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
F76L (p.Phe76Leu) variant details
- p.Phe76Leu
- ExAC rs772136444
- TOPMed rs772136444
- gnomAD rs772136444
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.40
- CADD 22.70
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available