E77D (p.Glu77Asp) variant of MAPK3 (P27361)
E77D (p.Glu77Asp) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
E77D (p.Glu77Asp) variant details
- p.Glu77Asp
- ExAC rs771108532
- gnomAD rs771108532
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.20
- CADD 15.70
- PolyPhen-2 0.01
- SIFT 0.66
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available