E50Q (p.Glu50Gln) variant of MAPK3 (P27361)
E50Q (p.Glu50Gln) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
E50Q (p.Glu50Gln) variant details
- p.Glu50Gln
- TOPMed rs2073033657
- gnomAD rs2073033657
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.08
- CADD 22.50
- PolyPhen-2 0.21
- SIFT 0.08
- Most common in the Latino/Admixed American population (allele frequency 2.5e-05)
- Structural context available