E27K (p.Glu27Lys) variant of MAPK3 (P27361)
E27K (p.Glu27Lys) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
E27K (p.Glu27Lys) variant details
- p.Glu27Lys
- gnomAD rs1302416785
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.10
- CADD 15.90
- PolyPhen-2 0.00
- SIFT 0.95
- Most common in the Latino/Admixed American population (allele frequency 2.6e-05)
- Structural context available