E13K (p.Glu13Lys) variant of MAPK3 (P27361)
E13K (p.Glu13Lys) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
E13K (p.Glu13Lys) variant details
- p.Glu13Lys
- cosmic curated COSV53773
- TOPMed rs1461921044
- gnomAD rs1461921044
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- REVEL 0.24
- CADD 21.20
- PolyPhen-2 0.01
- SIFT 0.79
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.9e-05)
- Structural context available