A6T (p.Ala6Thr) variant of MAPK3 (P27361)
A6T (p.Ala6Thr) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
A6T (p.Ala6Thr) variant details
- p.Ala6Thr
- ExAC rs753603085
- TOPMed rs753603085
- gnomAD rs753603085
- Missense
- Variant Prioritization Score for Impact Estimate 0.255
- REVEL 0.15
- CADD 18.90
- PolyPhen-2 0.00
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available