A69D (p.Ala69Asp) variant of MAPK3 (P27361)
A69D (p.Ala69Asp) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data and structural context.
A69D (p.Ala69Asp) variant details
- p.Ala69Asp
- ExAC rs768729666
- TOPMed rs768729666
- gnomAD rs768729666
- Missense
- Variant Prioritization Score for Impact Estimate 0.826
- REVEL 0.84
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available