A4V (p.Ala4Val) variant of MAPK3 (P27361)
A4V (p.Ala4Val) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
A4V (p.Ala4Val) variant details
- p.Ala4Val
- gnomAD rs1271627688
- Missense
- Variant Prioritization Score for Impact Estimate 0.257
- REVEL 0.18
- CADD 19.10
- PolyPhen-2 0.00
- SIFT 0.28
- Most common in the East Asian population (allele frequency 0.00028)
- Structural context available