A2V (p.Ala2Val) variant of MAPK3 (P27361)
A2V (p.Ala2Val) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
A2V (p.Ala2Val) variant details
- p.Ala2Val
- gnomAD rs1186880470
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.23
- CADD 19.60
- PolyPhen-2 0.00
- SIFT 0.21
- Most common in the REMAINING population (allele frequency 7.3e-05)
- Structural context available