A2G (p.Ala2Gly) variant of MAPK3 (P27361)
A2G (p.Ala2Gly) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
A2G (p.Ala2Gly) variant details
- p.Ala2Gly
- gnomAD rs1186880470
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.23
- CADD 21.30
- PolyPhen-2 0.02
- SIFT 0.18
- Most common in the East Asian population (allele frequency 0.00013)
- Structural context available