V20V (p.Val20Val) variant of MAP2K1 (Q02750)
V20V (p.Val20Val) in MAP2K1 (Q02750) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
V20V (p.Val20Val) variant details
- p.Val20Val
- gnomAD 15-66387407-T-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.422
- CADD 12.30
- Population evidence available
- Structural context available
- Dabrafenib and Cetuximab HT-29 cells, base editing z-scores (predicted consequen: score -0.678
- Literature evidence available